03-P046 Determination of the first lineages during mammalian embryogenesis
نویسندگان
چکیده
Wnt11/Pk1a-mediated planar cell polarity signalling orchestrates epithelial organ morphogenesis by regulating N-cadherin dependent cell adhesion forces Pablo Oteiza, Mathias Koeppen, Michael Krieg, Stephan Preibisch, Steffen Haertel, Daniel Mueller, Carl-Philipp Heisenberg, Miguel Concha 1 University of Chile, Santiago, Chile 2 Max Planck Institute for Molecular Cell Biology and Genetics, Dresden, Germany 3 BioZ, Dresden, Germany 4 SCIAN, Santiago, Chile 5 Gulbenkian Institute, Lisbon, Portugal
منابع مشابه
The Modern Primitives: Applying New Technological Approaches to Explore the Biology of the Earliest Red Blood Cells
One of the most critical stages in mammalian embryogenesis is the independent production of the embryo's own circulating, functional red blood cells. Correspondingly, erythrocytes are the first cell type to become functionally mature during embryogenesis. Failure to achieve this invariably leads to in utero lethality. The recent application of technologies such as transcriptome analysis, flow c...
متن کاملMaternal control of early mouse development.
The hiatus between oocyte and embryonic gene transcription dictates a role for stored maternal factors in early mammalian development. Encoded by maternal-effect genes, these factors accumulate during oogenesis and enable the activation of the embryonic genome, the subsequent cleavage stages of embryogenesis and the initial establishment of embryonic cell lineages. Recent studies in mice have y...
متن کاملO-44: Characterisation of Monotreme CaseinsReveals Lineage Specific Expansion of an AncestralCasein Locus in Mammals
Background: One important reproductive characteristic of Mammals is the production of milk to nurse the neonate. In order to better understand the evolution of milk we have investigated gene expression in milk cells from monotremes which are the most ancient representative of the mammalian lineage. Materials and Methods: Using a milk cell cDNA sequencing approach we characterise milk protein se...
متن کاملExpressional Analysis of Stem Cell Marker SALL4 in Mesencephalon during Chicken Embryogenesis
Background SALL gene family represent a group of evolutionary conserved zinc finger transcription factors which are involved in normal development. It includes four members (SALL1 to SALL4). SALL4 has significant roles in the maintenance of pluripotency and self-renewal, efficient proliferation /stabilization and cell fate decision of embryonic stem cells (ESCs). Our aim in this study was to a...
متن کاملP-24: Opioid and Progesterone Signaling Is Obligatoryfor Early Human Embryogenesis
Background: The growth factors that drive the division and differentiation of stem cells during early human embryogenesis are unknown. The secretion of endorphins, progesterone (P(4)), human chorionic gonadotropin, 17beta-estradiol, and gonadotropin-releasing hormone by trophoblasts that lie adjacent to the embryoblast in the blastocyst suggests that these pregnancy-associated factors may direc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Mechanisms of Development
دوره 126 شماره
صفحات -
تاریخ انتشار 2009